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Strain Development Scientist

Kasetsart University

Job Type

R&D

About the Role

We are looking for experienced scientists to join our Strain Development team to improve protein expression in microorganisms. You will be responsible for developing a strain improvement strategy and engineering strain for industrial production processes. You will also collaborate with a cross-functional team in a fast-paced, high-growth environment.

responsibilities

  • Develop strain improvement strategies.

  • Design and construct DNA expression and genome editing, analyze and improve of strain performance.

  • Conduct experiments and analyze data to assess growth conditions and protein expression of microbes.

  • Optimize metabolic and secretory pathway to maximize protein expression yield.

  • Develop a documentation system such as protocols, SOPs, and reports.

qualifications

  • M.S./Ph.D. in Bioengineering, Biotechnology, Molecular Biology, Microbiology, Microbial Genetics, or related fields with a minimum of 2 years of research experience.

  • Strong technical expertise in strain engineering, strain screening, methodologies, and related tools, as well as proficiency in microbial genetic engineering and molecular biology lab work.

  • A thorough knowledge of both prokaryotic and eukaryotic protein synthesis and secretion pathways in order to develop strategies for regulating and optimizing organisms' abilities to overexpress targeted proteins.

  • Experience with mass spectrometry/HPLC applications in at least one of the following areas is preferred: metabolic flux analysis, proteomics, metabolomics, lipidomics, or biomarker quantitation.

  • Be able to analyze data and display scientific creativity.

  • Ability to work independently as well as excellent organizational and planning skills are required. Eagerness to work collaboratively on a team of experts while adapting to the fast-paced needs of an early-stage startup.

  • Flexibility in working hours as required by experiments.

  • Good in English, both reading and writing.


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