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Downstream Processing Scientist/Engineer

Kasetsart University & Pathum Thani

Job Type


About the Role

We are searching for experienced bioprocess scientists/engineers to join our Bioprocess Development team to scale up the production process from bench to production scale. You will be in charge of designing downstream process purification in collaboration with industrial specialists.


  • Research and experiment with various equipment/technologies/materials to develop optimal downstream purification process for recombinant protein production.

  • Interact with cross-functional teams such as Strain Development and Product Formulation to share knowledge and transfer materials. Engage in inter-team feedback to drive iterative refinement of all processes toward product goals.

  • Participate in the tech transfer of production process to manufacturing scale, working effectively with third party manufacturers and parties. Participate in creating Tech Transfer documentation.

  • Review literature to make appropriate technical recommendations for application adoption.


  • M.S./Ph.D. in Biotechnology, Biochemistry, Biochemical Engineering, Chemical Engineering, Bioprocessing, Fermentation Engineer, Microbiology, or related discipline with a minimum of 2 years of experience in bio-process development is required.

  • Hands on experience in designing downstream processing, preferably recombinant proteins in microbial hosts.

  • Strong knowledge of purification and filtration process utilizing equipment and techniques such as AKTA, TFF, nanofiltration, microfiltration, UV-VIS, chromatography, etc.

  • Understand process development using DOE approach

  • Experience with detailed analysis of bioprocess data and demonstrate an ability to troubleshoot, debottleneck, and optimize bioprocesses at the unit operation and whole process level.

  • Strong computer skills including MS office and data analysis software is required.

  • Ability to work independently as well as excellent organizational and planning skills are required. Eagerness to work collaboratively on a team of experts while adapting to the fast-paced needs of an early-stage startup.

  • Flexibility in working hours as required by experiments.

  • Good in English, both reading and writing.

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